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Re: CFS and tianeptine SLS » SLS

Posted by linkadge on March 19, 2006, at 18:41:39

In reply to Re: CFS and tianeptine SLS, posted by SLS on March 19, 2006, at 9:07:50

I've personally been interested in tianeptine. It many of the rat studies tianeptine show a much more robust ability to protect certain brain structures from the consequences of unavoidable stress, than other antidepressants.

I expereineced a rebound improvement in depression after discontinuing SSRI's, TCA's and MAOI's. Infact, I went into a complete remission for about a month after stopping Parnate.

They're doing a lot of reasearch regarding the SERT molecule, and weather or not it is actually overactive in depression.

Some studies have shown that the opposite is true. Individuals carring a double short varient of the serotonin transorter, (which codes for lower serotonin reuptake) acutally had a higher lifetime prevailance of major depressive disorder.

We also have some drugs that act as serotonin uptake inhibitors, but have little to no antidepressant effect.

It's really a mystery to me.

Linkadge



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