Posted by yxibow on February 12, 2006, at 3:55:29
In reply to Whats best for GI problems, posted by linkadge on February 9, 2006, at 18:27:25
> I've been quite anxious lately. Mentally, the anxiety has not got to me much, but my stomach can't take it anymore. I'm sure I'm developing an ulcer.
> Has anyone had similar symptoms and found something that has been helpful ? SSRI's made the situation much, much worse.
Its worth noting that the vast majority of serotonin receptors are located in the stomach, in fact by some counts almost all. If you have an intense anxiety disorder, it is quite likely that you will have gastric upset. The chances of developing an ulcer are fairly low in this situation since ulcers are now known to be caused by H. pylori by Nobel Prize scientists.
If your insurance can afford it, a radical idea of using ondansetron (Zofran) or granisetron (Kytril) which are 5HT3 blockades could determine whether it is a serotonin issue or whether you indeed have a true ulcer, which is treated with a combination of antibiotics and proton pump inhibitors.
Meanwhile as others have said, stock up on pepto bismol. Its an old aid, but it does work, for whatever reason, it has both a mild antibiotic and anti-inflammatory action.
It is also worth noting that TCAs have been used successfully in IBS situations.