Posted by reefer on January 8, 2006, at 8:31:52
In reply to No More Cymbalta According to the Pdoc, posted by Phillipa on January 7, 2006, at 22:15:47
Hi Phillipa! I'm sorry you have been unable to tolerate most AD's. I had a hard time finding one also. Then one doctor suggested checking my metabolism. Genotyping was performed which showed i was a poor metaboliser of CYP2D6 which explains why i had such a hard time finding a med working for me. In my case we found that (es)-citalopram(lexapro) would probably be a good candidate since CYP2D6 had only minor impact on the metabolism of this medicine. And i've been on it ever since. It does it's job for my panic attacks but it's no cure. I still have pretty much anxiety and even though i don't really consider myself as having major depression i'm surely not the happy guy i used to be. That's where the buprenorphine comes in but that is another story(forum thread)...
Anyway my suggestion would be you do genotyping if you haven't already.