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Re: Haldol experiences?

Posted by Squiggles on November 11, 2005, at 13:13:17

In reply to Haldol experiences? Squiggles, posted by yesac on November 11, 2005, at 12:47:11

> Yes, but did the studies you found give any dosage information?

No, but I think you are right, i was sloppy.
I checked PubMed under


1: Cohen D, Diemont WL. Related Articles, Links
Abstract [Deterioration of schizoaffective disorder due to an interaction between haloperidol and carbamazepine]
Ned Tijdschr Geneeskd. 2002 Oct 12;146(41):1942-4. Dutch.
PMID: 12404911 [PubMed - indexed for MEDLINE]

2: Chou JC, Czobor P, Tuma I, Charles O, Bebe R, Cooper TB, Chang WH, Lane HY, Stone DL. Related Articles, Links
Abstract Pretreatment plasma HVA and haloperidol response in acute mania.
J Affect Disord. 2000 Jul;59(1):55-9.
PMID: 10814771 [PubMed - indexed for MEDLINE]

4: Chou JC, Czobor P, Charles O, Tuma I, Winsberg B, Allen MH, Trujillo M, Volavka J. Related Articles, Links
Abstract Acute mania: haloperidol dose and augmentation with lithium or lorazepam.
J Clin Psychopharmacol. 1999 Dec;19(6):500-5.
PMID: 10587284 [PubMed - indexed for MEDLINE]

6: Normann C, Brandt C, Berger M, Walden J. Related Articles, Links
Abstract Delirium and persistent dyskinesia induced by a lithium-neuroleptic interaction.
Pharmacopsychiatry. 1998 Sep;31(5):201-4.
PMID: 9832353 [PubMed - indexed for MEDLINE]

7: Sadeghipour-Roudsari HR, Farahani M, Shokrgozar AA, Farsam H, Dehpour AR. Related Articles, Links
Abstract Decrease in erythrocyte:plasma lithium ratio by concurrent administration of psychotropic drugs and lithium in mice.
Gen Pharmacol. 1998 Jul;31(1):63-6.
PMID: 9595281 [PubMed - indexed for MEDLINE]

8: Goldman SA. Related Articles, Links
Abstract Lithium and neuroleptics in combination: is there enhancement of neurotoxicity leading to permanent sequelae?
J Clin Pharmacol. 1996 Oct;36(10):951-62.
PMID: 8930783 [PubMed - indexed for MEDLINE]

10: Byerly MJ, Christensen RC, Evans OL. Related Articles, Links
No abstract Delirium associated with a combination of sertraline, haloperidol, and benztropine.
Am J Psychiatry. 1996 Jul;153(7):965-6. No abstract available.
PMID: 8659626 [PubMed - indexed for MEDLINE]

11: Goldman SA. Related Articles, Links
Abstract Lithium and neuroleptics in combination: the spectrum of neurotoxicity [corrected]
Psychopharmacol Bull. 1996;32(3):299-309. Erratum in: Psychopharmacol Bull 1996;32(4):544.
PMID: 8961772 [PubMed - indexed for MEDLINE]

12: Li R, Wing LL, Wyatt RJ, Kirch DG. Related Articles, Links
Abstract Effects of haloperidol, lithium, and valproate on phosphoinositide turnover in rat brain.
Pharmacol Biochem Behav. 1993 Oct;46(2):323-9.
PMID: 8265687 [PubMed - indexed for MEDLINE]

14: Yang YY, Deng HC. Related Articles, Links
Abstract [Influence of haloperidol on plasma Li+ and Li+ index]
J Formos Med Assoc. 1992 Sep;91 Suppl 3:S251-4. Japanese.
PMID: 1362913 [PubMed - indexed for MEDLINE]

16: Carvey PM, Kao LC, Zhang TJ, Amdur RL, Lin DH, Singh R, Klawans HL. Related Articles, Links
Abstract Dopaminergic alterations in cotreatments attenuating haloperidol-induced hypersensitivity.
Pharmacol Biochem Behav. 1990 Feb;35(2):291-300.
PMID: 2320636 [PubMed - indexed for MEDLINE]

19: Miller F, Menninger J. Related Articles, Links
No abstract Correlation of neuroleptic dose and neurotoxicity in patients given lithium and a neuroleptic.
Hosp Community Psychiatry. 1987 Nov;38(11):1219-21. No abstract available.
PMID: 2889659 [PubMed - indexed for MEDLINE]

20: Lowe MR, Batchelor DH. Related Articles, Links
No abstract Neuroleptic malignant syndrome or lithium neurotoxicity?
Br J Psychiatry. 1987 Oct;151:559-60. No abstract available.
PMID: 3447680 [PubMed - indexed for MEDLINE]
Items 1 - 20 of 68

---and more under "related links" and continuation-- just go to PubMed and enter;


> All I'm saying is that of course caution is warranted with ANY drug, but caution is also warranted when reading studies and other information you find on the internet.

I got some interesting results confirming that
dose plays an critical role in neuroleptic
malignant syndrome and other "extrapyramidal"?
reactions, according to dose. You are correct--
i was too general; still, I am such a chicken
that I would not mix neuroleptics or even
SSRIs with lithium.






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