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Re: Does Wellbutrin contribute to PMS? » lunesta

Posted by greenhornet on October 25, 2005, at 16:34:52

In reply to Re: Does Wellbutrin contribute to PMS?, posted by lunesta on October 23, 2005, at 14:50:20

> i am not a women but it makes sense. PMS is caused from a temp decrease in chemicals related to allpregnanolone, pregnanolone, progesterone, and ultimatly gaba-a receptor lowered. Welbutrin lowers the seizure threshold so its no surprise it would make PMS worse. It could also modulate allpregnanolone levels , as some antidepressants work just this way but usually positively, not negatively.

You bet there is a related effect with hormones and antidepressants. I was eight years POST menopause when I was started on Strattera. I had breezed through menopause (well sort of) But with the Strattera came the worst hot flashes immagineable -- and -- I would perodically spot as though I was having a period (which I had not had for ten years!! The docs all denied it then, but I believe they give it more credence today.


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