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Re: Klonopin and Seratonin... » spriggy

Posted by SLS on October 22, 2005, at 23:43:21

In reply to Klonopin and Seratonin..., posted by spriggy on October 22, 2005, at 17:16:53

Hi.

> I think I'm going to start up the Klonopin consistently again- I will probably keep it below .5 mg's. ( I usually cut a .5 in half).
>
> Anyway, someone once ( I think Maxime) said that Klonopin affects seratonin. Is this definite?
>
> I don't need anything to mess with my seratonin. It wigs me out.

Try not to get too wigged out about it.

Klonopin (clonazepam) does mildly to moderately depress some people, but it clears up as soon as the medication is stopped. You won't know until you try it. Since you haven't yet complained about it increasing your depression, I don't think you are being affected this way.

The investigative history of clonazepam includes contradictory findings regarding its affects on serotonin. I have always attributed its depressogenic effects to whatever serotonergic properties it possesses. However, there has been nothing I have read that would indicate any irreversible changes in serotonin funtion.

I have found other benzodiazepines to produce a temporary depression that lasts for a day or two. If you feel more depressed immediately, try not to come to any definite conclusions. Give it perhaps a week to see how a higher dosage of clonazepam will treat you.

Have you tried Neurontin as an anxiolytic?

I am still unclear as to what you are being treated for.


- Scott

 

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