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Re: remeron and cortisol 4wd

Posted by Elroy on October 17, 2005, at 13:03:59

In reply to Re: remeron and cortisol, posted by 4wd on October 16, 2005, at 22:41:59

I am not totally sure, but I don't believe so. I think that taking DHEA supplements can help promote a better DHEA-to-Cortisol ration... but doesn't necessarily LOWER existing cortisol levels... (also with the understanding of DHEA supplementation being within reasonable dosage ranges - DHEA can promote androgenic side effects in women and raise estrogen levels in males if taken at higher doses - like 50 - 100 mg daily).

Again, we're also talking about situations here where the patient doesn't simply have high normal cortisol levels from general day-to-day stress, etc., but situation where one's HPA Axis is dysfunctional and creating a hypercortisolism condition. If your cortisol levels were (let's say) twice the normal maximum of the reference range, what would the object of supplementation be? To get one's DHEA levels over twice the maximum of its reference range?

Generally DHEA-to-Cortisol ratio levels become an important issue when one has normal range cortisol but abnormally low DHEA. In those cases supplementation of DHEA (again, done very reasonably) would help re-establish the proper ratio, but whether that would aid in lowering anxiety levels, I couldn't say.

I know that often warnings are given with DHEA supplementation as far as taking it in the mornings as it can be "stimulating" and interfere with sleep. I know that sounds like Tyrosine to me. And I know that taking Tyrosine (in anything above 125 mg doses) increased my anxiety.

I am currently taking DHEA at the rate of 25 mg a day (12.5 mg in the morning and another 12.5 mg in early afternoon). At those levels it has not worsened my anxiety... but it has not improved it either.



> , you might want to check out the link message at:
> >
> >
> Hi Elroy,.
> After reading this article, I wonder whether taking DHEA supplements would help anxiety - if the problem is connected with an imbalance in the ratio between cortisol and DHEA?
> Marsha




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