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Re: remeron and cortisol - and Xanax.... 4wd

Posted by Elroy on October 17, 2005, at 12:50:27

In reply to Re: remeron and cortisol - and Xanax...., posted by 4wd on October 16, 2005, at 22:37:12

I am not aware of any studies showing that specific effect with Klonopin.

While I am sure that to some extent lowering anxiety levels will help moderate cortisol levels at least partially, it is clear - from this study - that Xanax has a specific anti cortisol effect beyond just its anti anxiety effect.

That is because the clinical study used healthy individuals (a combination of young adults and elderly persons as I recall), and tested their cortisol levels and DHEA levels following administration of the Xanax.

What was interesting was that DHEA-S levels remained unchanged while DHEA levels increased and cortisol levels decreased. That would clearly indicate that the Xanax was performing some type of process of converting the cortisol to DHEA (as otherwise an increase of DHEA-S would be needed to account for the increased DHEA).

Elroy


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