Psycho-Babble Medication | about biological treatments | Framed
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Just started Nardil

Posted by CK1 on October 15, 2005, at 16:13:07

Hi all,
In case some of you don't know, my main problem is social anxiety and atypical depression (sleep 10 hrs night, always hungry, apathetic, unmotivated). I was on Paxil for 3 yrs (worked great) but it pooped out 8 months ago. Tried 4 SSRI's since then and either had bad side effects or no response.
I'm seeing a new doctor (an Emory University MD) and had my first appt yesterday and he says there is 2 reasons for "poop out."
1) Dopaminergic reduction caused by long term SSRI usage, in which case a dopaminergic drug like Wellbutrin will help the user regain the initial good response
2) Soft Bipolar or subsyndromal bipolarity

He thinks that there is a higher chance that I will respond to Nardil than the other SSRI's, but, even if I do respond, he believes it will someday "poop out" maybe in 6 months or 5 years, no one knows. But, if I do respond, we're going to "ride the wave" for as long as possible before adding anything.

I've never had ANY bipolar-like manic/hypomanic episodes, but I do believe my non-response after an initial good response to an SSRI puts me in the catagory of "subsyndromal bipolarity".

If Nardil doesn't work, he wants me to go back to Paxil (which doesn't work anymore) and add low dose Seroquel. He says adding anti pyschotics is a very common treatment regime nowadays for treatment resistant depression/anxiety.

Has anyone had experience with SSRI Poop Out and have they been stabilized (long term) by either mood stabilizers/antipyschotics/MAOI's? I want something thats going to KEEP me better, not better for a year or two and then worse. He has me convinced that even if Nardil works, it won't work long term!

On a lighter note, I've been on Nardil for 2 days with no side effects. I'll update after a full week.



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Psycho-Babble Medication | Framed

poster:CK1 thread:567234
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