Posted by zeugma on October 9, 2005, at 17:06:10
In reply to Re: Help!! mom needs serious help, posted by linkadge on October 9, 2005, at 16:49:03
> Could you ballpark a dose that might replace say 150mg of mellaril ?
since according to the reference I have the two drugs have similar dose ranges, i suppose 100-200 mg seroquel is similar to 150 mg mellaril.
Seroquel is weaker at the D2 receptor than mellaril. But its ratio as far as I can tell among D2, muscarinic and serotonin 2A blockade is roughly equivalent to Mellaril's (both drugs within a range of 2:1 among those 3 receptors). Zyprexa is about 6 times more potent at the muscarinic than D2 receptor.
Is your mother's dr. totally clueless? That is a scary thought.
also, what do you think of Ed's advice? I'm sorry, I am very uncomfortable giving out pharmacological advice.