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Re: you could try zyprexa

Posted by iforgotmypassword on October 6, 2005, at 23:05:25

In reply to Re: you could try zyprexa iforgotmypassword, posted by gardenergirl on October 6, 2005, at 22:46:18

>How does zyprexa help depression? Is it the anxiolytic properties? I do have an anxious component to my depression.

I think sort of, that and it's supposed to have anti-rumination effects... but also it blocks the 5-HT2a receptor, which is a receptor when stimulated is supposed to cause apathy and amotivation. not only that but i believe that it's stimulation also increases cortisol levels, which is supposed to cause all sorts of nasty depressive effects... but i am just guessing that 5-HT2a (and 5ht2c possily) blockade is its main therapeutic method. and blocking the 5HT2 receptors is supposed to improve prefrontal cortex and dopamine function which can only be good. then theres the dopamine receptor blockade which may actually be a good thing at low doses if it mainly just targets the autoreceptors... also zyprexa is supposed to be the least antidopaminergic antipsychotic so there may be less cause for worry that it will harmful in that respect. but again, im only guessing. i hate these drugs. :( its so counfusing.


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URL: http://www.dr-bob.org/babble/20051003/msgs/563922.html