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Re: GABA meds other than benzos? » willyee

Posted by Chairman_MAO on September 9, 2005, at 0:05:24

In reply to Re: GABA meds other than benzos?, posted by willyee on September 6, 2005, at 17:06:07

Most anticonvulsants do not affect gaba. The one common thing nearly all of them do is actually fast sodium channel blockade.

Tegretol does not affect GABA. Neurontin only increases GABA synthesis; otherwise it affects Ca++.
Topamax has weak gaba-a potentiation.
Depakote is the only one here that I would say has gabanergic activity powerful enough to be useful in psychiatry as a gabanergic agent (SSADH and GABA-T inhibition and increased gaba synthesis possibly, IIRC).


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URL: http://www.dr-bob.org/babble/20050901/msgs/552549.html