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Re: How I feel on high-dose SSRIs

Posted by Dave001 on September 1, 2005, at 1:31:10

In reply to Re: How I feel on high-dose SSRIs » Dave001, posted by zeugma on August 28, 2005, at 5:33:23

> There is some evidence, too, that disorders traditionally
> conceptualized as OCD-like, such as skin picking and
> trillichtromania,

But isn't there a difference between e.g., someone who has a conscious
obsession with depilating his/her body, and someone who has a proclivity
for nervous habits such as biting his/her nails?

> are more closely related to dopaminergic dysregulation, which is
> intuitively sensible, since these are disorders of embodiment.

Perhaps, but is it a matter of too much or too little dopamine, or both?
And couldn't dopamine be only a marker or consequence of some other
process? Or maybe downstream processes modulate behavior. It seems
plausible that increasing or decreasing dopamine concentrations is
regional and/or receptor specific, and that one might want to manipulate
concentrations differently, even oppositely, depending on the brain
region and receptors. I gave up trying to speculate from biochemistry a
long time ago. The more that I learn, the more I appreciate how VERY
little is known about human biology, especially the brain.

> -z


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poster:Dave001 thread:544795
URL: http://www.dr-bob.org/babble/20050827/msgs/549550.html