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Re: Help Ed, Linkage, Scott, or another med jedi.

Posted by SLS on August 18, 2005, at 6:55:21

In reply to Re: Help Ed, Linkage, Scott, or another med jedi. SLS, posted by EERRIICC on August 18, 2005, at 2:20:15

> What do you think could stop this parnate poop-out (three months every time)

I don't know, but if you figure it out, I want to be amongst the first to know!

> Naltrexone, DA's, Memantine, Ritalin, bloodletting, appeasement of angry gods?

All good ideas...

:-)

Naltrexone is interesting. However, I know of only one person on PB who reported its successful use as an augmentor of Prozac (20mg Prozac and 25mg Naltrexone).

Memantine is theoretically interesting. Unfortunately, I haven't seen a preponderance of people report having success with it as an agent to prevent tolerance to stimulants. I experienced a brief antidepressant response to it last year. Perhaps the manipulation of NMDA glutamatergic neurotransmission by memantine and other drugs has some utility in treating depression, but there is a paucity of even anecdotal data to support this. The NIMH has been conducting trials of memantine to treat major depression. I don't know what have been their results.

Ritalin is a drug that I have tried in combination with Parnate. It did nothing for me. I think it might make a good augmentor when there is residual low energy, but probably does not confer a robust antidepressant effect when placed in this role.

In the past, bloodletting and appeasement of angry gods have demonstrated too high a placebo effect to yield meaningful results. People often claimed remission even before the first blade was unsheathed.


- Scott

 

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poster:SLS thread:542766
URL: http://www.dr-bob.org/babble/20050816/msgs/543345.html