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Re: Keppra (levetiracetam) for bipolar disorder? zeugma

Posted by SLS on August 17, 2005, at 18:46:16

In reply to Re: Keppra (levetiracetam) for bipolar disorder? SLS, posted by zeugma on August 17, 2005, at 16:29:03


It looks like you have established a hypocretin connection to your condition given the narcolepsy and appetitive depression you have observed and the way they are influenced by modafinil. You might want to begin looking at the way the X and Y clocks are synchronized and see if there is some way to cue or reset them using environmental stimuli like a light box or well-timed melatonin ingestion. From what I understand, depression can affect adversely the periodicity of hypocretin secretion.

As far as Zyprexa is concerned, many people on PB have described it as producing or enhancing "clarity" of thought or thinking more clearly. I myself experienced this when I added it to help control an antidepressant-induced mania. I think Zyprexa has a positive influence on executive function in areas that might also contain hypocretin neurons such as PFC.

For me, Abilify has increased motivation and mental energy. It has also protected me from suicidality by dissipating anxious catastrophic thinking.

- Scott




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