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Re: is SEROQUEL better than ZYPREXA for depression?

Posted by blueberry on August 14, 2005, at 10:50:45

In reply to is SEROQUEL better than ZYPREXA for depression?, posted by bipolarspectrum on August 13, 2005, at 2:37:45

There is no way to tell whether seroquel or zyprexa would be better for depression. We all respond so individually. In either case, they seem to work a lot better than on their own when combined with a small dose ssri, most especially prozac. I do know that zyprexa helps my depression quite a bit, in combo with 10mg prozac, but that seroquel actually created depression for me.

Seroquel sedation is generally stronger than zyprexa sedation. In either case, the sedation does ease off over time. I've taken 5mg zyprexa for a long time. At first it was quite sedating. Now it helps me get to sleep (about 4 hours after dosing), and provides excellent sleep, but it has zero sedation during the day.

Changing the dosing time can help. If you take it too close to bedtime, then there can be a lot of sedation carryover into the next day. I have found that taking zyprexa at 5:00pm is the best for me. It helps me relax in the evening, and then I'm ready for bed about 4 hours later.

Hope this helps a little.


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