Psycho-Babble Medication | about biological treatments | Framed
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Re: schitsophrenia NMDA and lithium

Posted by SLS on July 12, 2005, at 18:51:27

In reply to schitsophrenia NMDA and lithium, posted by linkadge on July 12, 2005, at 18:11:38

> I read an article that suggested that schitsophrenia might be caused by low activity of NMDA. It suggested that ketamine and PCP were able to elicit psychosis because they were NMDA antagonists.
> Why then, is lithium, an NMDA antagonist often used in schitsophrenia ?

I must be missing out on the current treatments of schizophrenia. I thought lithium was of little value unless the actual disorder was schizoaffective. I'll peruse Medline and see what's happening with lithium and schizoid disorders. It's possible that the degree to which lithium interacts with NMDA receptors is small enough to be negligible.

- Scott




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