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Re: COMT Inhibitors for mood disorder? » ed_uk

Posted by rod on July 2, 2005, at 18:38:24

In reply to Re: COMT Inhibitors for mood disorder? » rod, posted by ed_uk on July 2, 2005, at 14:17:39

Hi Ed :-)
>
> >It was more like a downer on the long term....
>
> It made you more depressed?

Not really depressed.
I dont find the right words for this.
Maybe the word "blah" is the right one for this feeling :-)
It was neiter great nor bad. An other person also said it made him a couch potato... I guess its due to downregulation of postsynaptic D receptors.
For me, Mirapex was a waste of time...

> Are you interested in trying other dopamine agonists eg. cabergoline?

not at the moment. I think they are a waste of time for depression, because they seem to always "poop out"....

I havent seen any person on this board who found them effective for a longer period of time....

I like the COMT inhibitors better, because they do a lot more than just dopamine..
And hope they do the trick for me!

mfg :-D

Roland



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