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Re: To Mr Scott - More questions for you » ed_uk

Posted by SLS on June 28, 2005, at 13:54:55

In reply to Re: To Mr Scott - More questions for you » SLS, posted by ed_uk on June 28, 2005, at 11:58:45

> Fatigue, dizziness, headache, nausea, anxiety and somnolence were the most common adverse events during combined administration

> The combination may even be better tolerated than either drug alone.

This might reflect the increase in 8-hydroxymirtazepine brought about by Paxil coadministration. This effect is similar to what happens when one increases the dosage of Remeron from 30mg to 45mg. Many of the side-effects that occur at the lower dosages begin to disappear, presumbably as the proportion of NE alpha-2 blockade increases. Just a guess.


- Scott

 

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