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Re: Ascendin SLS, MedEmpowered » yesac

Posted by SLS on June 6, 2005, at 5:10:56

In reply to Re: Ascendin SLS, MedEmpowered, posted by yesac on June 6, 2005, at 0:40:58

I never much cared for the idea of using a single medicinal preparation containing an antidepressant with a antipsychotic. I think it can make a mess of things. It would be better to titrate each independantly to optimize treatment. However, Asendin is a single drug with multiple sites of action. It just might have the right proportion of effects to do the job.

It is difficult to say whether or not Asendin will be more or less problematic with micturition (initiating urination) than desipramine was. Although both are anticholinergic, the more potent NE properties of desipramine probably amplify some of these side effects. In any event, knowing that you have a sensitivity for side effects would argue in favor of a very slow titration.

How did you go about initiating and titrating desipramine?


- Scott

 

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