Posted by SLS on June 5, 2005, at 14:12:45
In reply to Ascendin, posted by yesac on June 5, 2005, at 13:37:04
> Has anyone taken Ascendin (amoxapine)?
>
> I'm looking for something to add to lithium, especially if I go off Seroquel.
>
> Ascendin seems kind of unique and different. You never hear much about it though, which makes me wonder.What attracts you to amoxapine?
Med_Empowered recently commented that he thought loxapine was a unique antipsychotic worth consideration in certain situations. Perhaps he can expand on that a bit here. Amoxapine is a derivative of loxapine and retains much of the antpsychotic properties of the parent compound in addition to its antidepressant properties as a tricyclic. Unfortunately, amoxapine shares with loxapine a risk of developing EPS. This was evident as early as the pilot studies.
I tried amoxapine when it was first approved in 1982. I didn't like it. It dulled me in ways that my illness doesn't tolerate well. I was particularly annoyed by the decrease in libido that amoxapine produced. Like most of the other TCAs, anticholinergic effects were significant.
- Scott
poster:SLS
thread:507989
URL: http://www.dr-bob.org/babble/20050601/msgs/507999.html