Psycho-Babble Medication | about biological treatments | Framed
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Re: Dexamyl

Posted by Chairman_MAO on April 26, 2005, at 12:19:34

In reply to Re: Dexamyl, posted by vivi on April 21, 2005, at 21:36:40

Dexamyl no longer exists because it actually elevated mood. Virtually no currently marketed antidepressants actually work--they simply make one number to their own emotions. And if you're numbed up, you can't be depressed, can you? It's sick stuff.

The MAOIs, are IMO (I am not at all humble on this topic) are the only drugs on the market--marketed as such--worthy of the title "antidepressant". That is, they actually ELEVATE mood. Furthermore, there will be no more effective monoaminergic antidepressants coming--EVER--because in order to be truly effective, you've got to affect DA, which makes an "abusable" drug. Even the benign, virtually abuse-proof buprenorphine is now a CIII controlled substance. It's pathetic.

Any new antidepresssant that actually is effective will use neurotransmitter systems heretofore untouched by psych drugs, such as neuropeptide Y and CCK (for depression and anxiety). New effective anxiolytics will probably be neurosteroids, such as allopregnanolone derivatives (see ganaxolone). Selective opioidergic mechanisms will also be on the menu someday, I hope.




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