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Advice: Selegiline + (Depakote/Seroquel)?

Posted by cache-monkey on April 26, 2005, at 0:41:02

Hey all,

So, I need to make some moves in my med regimine. Not feeling so good lately. I'm cycling a little. I think I'm possibly BPII, but this is all cycling amongst the bad stuff: anxiety, dysphoria and depression. Also prominent are anhedonia and asociality. My pdoc has me on Depakote ER 1000 mg/day and Ativan 3 mg/day and I feel more depressed.

At some point I'd like to try low-dose (MAOB selective) selegiline as an add on, which I would like to do at some point regardless. My "normal" state exhibits dysthymia and a reliance on nicotine, so that might be something useful for that.

My anxiety is being kept in check mainly by benzos, and the Depakote isn't really doing much in that department. Nor is it helping my dysphoria. So, Seroquel seems kind of promising for the dysphoria, depression, cycling, and could help against anxiety w/o relying a benzo. (I'm really liking what I've read coming out of Calabrese's recent studies on Seroquel.)

So, I'm thinking either:
a) just add selegiline to the Depakote
b) drop Depakote, add seroquel, then see about adding selegiline
c) keep the Depakote, add seroquel, then see about adding selegiline.

Any advice here? Particularly, has anyone tried selegiline with either Depakote, Seroquel, or possibly both?

Thanks!
cache-monkey


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poster:cache-monkey thread:489624
URL: http://www.dr-bob.org/babble/20050423/msgs/489624.html