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Re: opiates, my cure for depression linkadge

Posted by jerrympls on February 22, 2005, at 18:09:06

In reply to Re: opiates, my cure for depression, posted by linkadge on February 20, 2005, at 9:50:55

> Opiates will surely cure depression. They are perhaps the final common molecular destination to pleasure in all sentiant life.
>
> Unfortunately, I have not met anyone who has not *completely* adapted to the effects of opiates.
>
> I'd stay away from them, just in the sence that I just can't see how it would last. Ask Mathew Perry ("Friends") He went through excrutiating rehab after slowly increasing his vicodin prescription to treat depression.
>
>
> I could be completely wrong, but I don't think opiates are a long term answer by any means.
>
> Plus I don't think that an antitolerance meds really work. GLutamate blockers might block the tollerance to the drugs but they can also block the subjective effects of the drugs, by blocking glutamate activity in the Neucleus Accumbens and at the medium spiny neurons.
>
> The only reason I am so adiment is because a little while back I treated my depression with Codiene 30mg tabs. I titrated up to 120mg/day.
>
> After a week (somtimes less) of any dose increase, I would feel no effect. To make things worse, opiate withdrawl caused the *most* profound depression I can even discribe.
>
> You become *hypersensitive* to all pain, physical and emotional.
>
> I'm not trying to bum you out, but I just don't want you to experience what I did.
>
>
>
> Linkadge
>
>
>

Hi Link-

I agree with your post - and these are the things that my doc and I went over. We agreed the benefits outweighed the risks of tolerance & dependance. I don't think it will be a long-term treatment option - but stranger things have happened.

So far, it's been 2 months on opiates - and no need for increase in dosage. I don't feel them when I take them - they just keep the floor from falling out from under somehow. Yes, I am scared of the depression that follows opiate withdrawl and I guess I'll have to cross that bridge when or if I ever get to it.


Thanks
Jerry


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URL: http://www.dr-bob.org/babble/20050222/msgs/461926.html