Posted by barbaracat on February 22, 2005, at 14:59:26
In reply to Re: Cymbalta from a BP-II - dose question » barbaracat, posted by Ritch on February 21, 2005, at 21:28:23
Thanks for the math, Ritch. That's pretty good. Could you describe what your experience was on Cymbalta? I'm curious because I was also on high doses of seroquel and wonder how someone else's experience compares. Did you have the 'claw' like tension in your neck, occiput and throat? Was your hypomania the fun productive kind or anxious and a little insane? (Mine was definitely insane).
> Each one of those Cymbalta pellets is .1mg, so if you take ten pellets it is 1mg. I *started* at 3mg (30 pellets) and got an immediate hypomanic reaction. It kind of settled and fluxed over the course of a couple of weeks, but ended up making me panicky and it didn't get better. I tried *lower* doses which helped, but ended up off the stuff. I don't think it is so much the 5HT/Ne reuptake inhibition levels, I think it is a difference in affinity to agonize different receptor subtypes (super wild guess). Whew, if I would have taken 30mg all-at-once, I would likely have similar or worse problems that you are having.....