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Re: Interested in Nortriptyline... Side Effects? » cache-monkey

Posted by zeugma on February 18, 2005, at 17:40:28

In reply to Re: Interested in Nortriptyline... Side Effects? » zeugma, posted by cache-monkey on February 18, 2005, at 12:11:37

> Thanks for the other info! Could you please clarify what "anti-muscarinic" means?
>
> Best,
> cache-monkey

Muscarinic receptors are a species of acetylcholine receptor, and the anti-muscarinic effects of TCA's are held responsible for the 'dumb-drug' effects of the drugs. They are involved in cognition and memory processes. Their blockade is also partly responsible for the constipation/dry mouth side effects. Their blockade also arguably adds to the AD effect.

-z
>
>
>

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