Posted by Ritch on February 12, 2005, at 12:50:21
In reply to Re: need TCA advice, posted by linkadge on February 12, 2005, at 12:03:08
> Where does clomipramine fit into the picture?
>
> The only reason I am concerned is that if I swich abruptly from a SSRI Zoloft to a NRI, like nortrip, this might be a big change.
>
> LinkadgeI wouldn't write off amitriptyline too quick since it has the benefits for migraine prophylaxis *and* also has a significant amount of serotonergic activity. It *is* very very sedative though on start up. However, I found doxepin to be more sedative than amitrip. Also, from what I remember .. the last time I was on amitrip. was just 10mg twice daily and I definitely noticed an improvement in focus and attention, but it was slow in coming.. it took nearly a month. The reason I stopped it was oddly enough a lack of impulsive spontaneity that other people commented about.. it definitely didn't seem to make my bipolar worse.. I can see where it would be a good ADD med for some.. if you can tolerate it the start up and it doesn't cause too much postural hyotension, etc. Nort. worked good on ADD sx also, but with less side effects (no postural hypotension and could take it easily in the day).. but the amitrip. seemed a lot more anxiolytic. Never tried clomipramine. Tried imipramine and didn't like it. Tried desipramine, but it *caused* too much anxiety. There are people that take a mix of *both* amitrip. and nortrip. to balance the benefits and s/e's of each one.
poster:Ritch
thread:456737
URL: http://www.dr-bob.org/babble/20050212/msgs/456785.html