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Dextromethorphan+Lamictal+Wellbutrin = Interact?

Posted by Lonely on January 30, 2005, at 23:37:31

My hubby is on Lamictal 50 mgs. a day for BP2. He's also on Wellbutrin 300 mgs a day.

For the past 3 weeks he's been coughing like crazy, it was unproductive for quite a while, then he starting coughing up clear stuff. But, he couldn't eat or sleep or talk without having a choking cough and turning purple. No fever, no sign of flu or cold so we think it's a hyper allergic state for the first time in his life. He also has MS.

After going to an ENT who acted like nothing was wrong and telling his neurologist who ignored my question, we gave him Allegra which dried him out, 4 days of decreasing Aristocort (now he has hypoglycemia) and finally, today, added an over-the-counter Dextromethorphan with guifenesin which did ease the coughing but left him with what he described as the bad side of being drugged but none of the pleasant side effects. He's pretty agitated and hyper.

Okay, the question is and I haven't been able to find this on the net ... does the ingredient in the cough med - Dextromethorphan - interact w/Lamictal and/or Wellbutrin? His agitation and choking and the lack of interest from doctors is driving me crazy. Will the cough drug aggrevate the bipolar?

Also, is coughing and choking typical of a bipolar 2? I sure haven't heard of such a thing. Ironically, when he was on Trileptal, and was coughing from previously using ACE inhibitors, he got better re the coughing. So, I'm wondering if there is a "brain" or "neurological" component to all of this?


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poster:Lonely thread:450411
URL: http://www.dr-bob.org/babble/20050128/msgs/450411.html