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Re: Do MAOIs make normal people high? » Don_Bristol

Posted by King Vultan on January 11, 2005, at 12:09:43

In reply to Do MAOIs make normal people high? » King Vultan, posted by Don_Bristol on January 11, 2005, at 9:48:06


>
>
> Todd, I recall reading somewhere that taking SSRIs can cause very vivid dreaming (or nightmares).
>
> It was this which made me think that vivid deaming can have a clear biochemical origin. And then I figured that it may not be so outlandish to think that if the biochemistry caused by the SSRIs were reversed then it might result in reduced vividness.
>
> In my friend's case her extremely vivid dreaming pre-dates her SSRI, Lexapro, by a very long time so I don't think there is any cause & effect there. I believe it is just a co-incidence.
>
> But I am left with the question, how can she reduce the extreme vividness of her dreaming by using meds?


Probably the biggest reason Nardil reduced my dreaming so much was its effect on norepinephrine. Increasing norepinephrine transmission generally seems to cut down on dreaming, based on what I've read and from my own experience with various drugs. Desipramine was probably the 2nd strongest of the drugs I've been on as far as reducing dreaming, and this is a very powerful and selective norepinephrine reuptake inhibitor. I have not done a lot of research on the subject of nightmares, as I really do not get them, but there are probably therapies that have been developed for this.

In response to your question about MAOIs in the subject line, I've read that they can have a mood elevating effect even on non-depressed individuals. I'm not sure I necessarily agree with that, and being a chronic depression patient, I have no way to judge its validity personally.

Todd


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poster:King Vultan thread:440197
URL: http://www.dr-bob.org/babble/20050108/msgs/440649.html