Posted by Larry Hoover on January 11, 2005, at 11:12:43
In reply to Re: Methamphetamine vs N-acetyl-l-cysteine » JayDee, posted by CareBear04 on January 10, 2005, at 22:56:12
> sorry, i don't have the brainpower right now to make it through the abstracts, but all i can say is AVOID n-acetylcysteine! if i remember right, it's aka "mucomyst," which is the most disgusting thing that has ever gone through my body. it was administered as an antidote to too much tylenol, and it is the most foul stuff ever! sorry i couldn't read the article, but all i can say is that i would take meth, crack, or anything else over the n-acetylcysteine!
They were saving your life. Liver failure is an absolutely horrible way to go. You can't imagine it. It is far far worse than swallowing oral NAC.
Tylenol (acetominophen/paracetamol) destruction in the liver requires one molecule of glutathione for every molecule of tylenol. If you use up all the glutathione, the liver cells are programmed to self-destruct, via a process called apoptosis. It is the rupturing liver cells that kill you. Not only does your liver fail to work, but all those enzymes that weren't destroyed are loose in the body. It's not pretty. NAC directly stimulates glutathione formation, in a dose-dependent manner.
Taking a tylenol overdose induces a situation something like firefighters responding to a fire with a pumper full of water. When they run out of that water, they can no longer fight the fire. The doctors were giving you massive amounts of oral NAC, analogous to the firefighters hooking up to a hydrant. By having an unlimited supply of water/NAC, the firefighters/liver cells can do their job.
Lar
poster:Larry Hoover
thread:439943
URL: http://www.dr-bob.org/babble/20050108/msgs/440631.html