Posted by rainy on December 26, 2004, at 14:15:35
In reply to Re: Topamax and metabolism » bridgey1128, posted by headachequeen on December 24, 2004, at 16:42:33
Kat, I just read this morning in Newsweek of all places (prescribing info for Topamax, big ad for migraine relief) that Tegretol reduces blood plasma levels of Topamax by 40%. I'm sure your medicine man is aware of this, but you aren't getting as much Top by almost half as you may have thought you were. Unless you already knew this. Hence the continuing seizures??
The friendly supermarket pharmacist confirmed this fact and stated this is true with trileptal as well--something I want to ask my pdoc about as a mood stabilizer. Hoo boy.
As for titrating up on Topamax, I'm on day three of 350 mgs and noticing that I'm beginning to have repetitive thinking--the same sentence keeps running through my head, or I rehearse conversations over and over, always taking the same part. Sort of like learning lines. Bleahg.
At least so far I'm not as mean and nasty as I was last time I went up, but this is as far as I got, too. Pdoc expects me to be at 400 by now, I think--she didn't instruct me. I saw her three weeks ago and have an appointment on Wednesday. I'm really dreading the appointment.