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Antiparkinson drug as antidepressant?

Posted by blanding on December 22, 2004, at 18:52:59

A review of the literature indicates that the anticholinergic antiparkinson drugs can be abused by some patients to achieve pleasurable effects ranging from a mild euphoria with increased sociability at the lower doses to a toxic anticholinergic psychosis with disorientation and hallucinations at higher doses. Trihexyphenidyl may have a greater potential for abuse but there has been no systematic data on this issue. While the abuse of these drugs may not be widespread, it is yet another factor arguing for their judicious use.

My question is: Has anyone successfully 'abused' any anticholinergic antiparkinson drug for treating depression — solely or as augmentation?


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poster:blanding thread:433064
URL: http://www.dr-bob.org/babble/20041217/msgs/433064.html