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Re: Opioid analgesics in the treatment of depressi

Posted by paulbwell on December 19, 2004, at 17:13:41

In reply to Re: Opioid analgesics in the treatment of depressi, posted by lew on December 18, 2004, at 9:52:38

> I am looking for a TCA to go with my opiate therapy treatment. Someone on this sight posted that TCA's were a good combo to use with opiates. Which one is the best? with the least side effects, weight gain, loss of libido, etc.

Hi lew,

I have taken a TCA for 2 months now. I use Codeine for its acute acting anti- depressant anti-anxiety effects, it sometimes works very well, quite frankly better than many ADs or benzo's i,ve taken, something akin to a combo of both, in a synegestic manner.

I dont know where you live, but in Australia, the UK, New Zealand, theres an OTC product that contains a reasonable amount of codeine in it, which is easily separated from its other compound. Since starting this TCA i've found Codeine somewhat less effective than before, (althought according to the PDR this TCA apparently potentiates Opiates, Benzos??) but other Opiates-Opiodes which dont have to be metabalised into 10% morphine (such as Codeine), may be different. I,v tried Codeine (200-300-400mgs) with 20-30mgs Valium or 2-6 mgs Clonazapam and have at times, experienced acute psychic relief, where stress, anxiety, being replaced with a warm, calm, every-things ok type feeling, reminesant of childhood.

So yes all the 1990s theories of lack of Seretonin being the cause of depression, i think it's just as likely *some folks* do have abnormal Endorphin function, as alluded to in the above posts, where these people becoming well, with controlled Opiate-Opiode therapy bringing about excellent response.

Cheers

Good Health


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