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Re: Eszopiclone ed_uk

Posted by jrbecker on December 16, 2004, at 14:09:24

In reply to Re: Eszopiclone jrbecker, posted by ed_uk on December 16, 2004, at 12:01:10

good question Ed. The company postulates that due to Eszoplicone being a stereoselective (S) isomer of the zopliclone molecule, it is associated with greater efficacy and less side effects.

Of course, we've seen this before in the Lexapro/Celexa debacle.

However, from what I've read, eszopiclone IS a more potent and pharmacologically superior form of the drug. But we will have to separate fact from spin once the drug hits the market.

The following might provide some more background...

http://www.trends-in-medicine.com/June2003/Sleep063p.pdf

http://www.trends-in-medicine.com/Feb2003/Insomnia023p.pdf


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URL: http://www.dr-bob.org/babble/20041211/msgs/430328.html