Posted by darkhorse on November 19, 2004, at 9:03:05
In reply to Re: Treatment in England, posted by ed_uk on November 19, 2004, at 8:20:54
> Hi Adam,
> Most prescriptions for TCAs in the UK are for low doses. Part of the reason is because they're widely used for insomnia and neuropathic pain but even the doses used for depression are low. It's rare for anyone to take more than 75mg a day of most tricyclics eg. dothiepin and amitriptyline, the two most widely used TCAs. For a long time, dothiepin was the most popular AD in England! Lofepramine, however, is given at higher doses 140-210mg/day.
Thanks for the useful info....I do not know why all american books which deal with psychotropics states normal doses for TCA's are to reach 150mg,and increase if no response to 250-300mg,and that 50-75mg are considred low,ineffective dose ??...do u have an explanation for this?