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Re: Tricyclic ADs vs. SSRIs » jboud24

Posted by jujube on October 31, 2004, at 19:14:22

In reply to Re: Tricyclic ADs vs. SSRIs, posted by jboud24 on October 31, 2004, at 18:59:51

Unfortunately, the pdoc I see doesn't seem to keen on combining ADs. I, myself, am not too keen on another 8 week trial, but if that's what I have to do, then so be it. I just hope I can have some relief before Christmas. I don't want to ruin Christmas too (haven't been very present for any celebrations, birthdays, Thanksgiving, etc., for the past number of months). By the way, I thought Nardil was a MOAI?

My appointment is on Tuesday as well. I am not the most open person when it comes to my emotions, even with the pdoc, so I don't think he is completely aware of how bad I am feeling. In my family, everybody else was allowed to be upset, sad, anxious, but I always got the "what have you got to worry about. Your problems are nothing compared to what I am going through.". Nobody wants me to be sad or sick or anything but available and supportive. So, I've learned to just deal with things myself, and keep a smile on my face. And, I am generally a happy person who can let things roll off there back. But not now or for the past number of months, and it is scaring the crap out of me. Oh well, I think the pdoc will run out of kleenex by the time my hour is up next week. Sorry to ramble.

Good luck to you with your new pdoc and at your appointment on Tuesday. I hope all goes well. Who knows, perhaps we will be comparing notes next week.

Take care and thanks.

Tamara


> TCA's are probably better than SSRI's for anhedonic depression due to their effects on norepinephrine reuptake inhibition. Desipramine has the strogest and most selective profile in regards to the NRI effects. Clomipramine possesses them as well, but it is more of a dual reuptake inhibitor.
>
> Perhaps combining a selective SSRI like Zoloft or Celexa with a selective NRI TCA like desipramine would be something to look into. You would probably risk less hypotension and dizziness with such a combination.
>
> Good luck with your doc, my next appointment is Tuesday with a new pdoc. I'll be asking for a trial of Nardil and Klonopin. I'm tired of the monoamine reuptake inhibitors, they dont seem to be cutting the proverbial mustard for me.
>
> Justin


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poster:jujube thread:409651
URL: http://www.dr-bob.org/babble/20041029/msgs/409761.html