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Re: Anybody else experience this? » jujube

Posted by karaS on October 31, 2004, at 16:50:33

In reply to Re: Anybody else experience this? » RetiredYoung, posted by jujube on October 31, 2004, at 15:57:54

> Thanks. I think, at this point, I am leaning that way. Perhaps after now having been on three other ADs, the Paxil may work. I am so afraid of the side effect profile of TCAs, but I will not discard them as an option. My depression this time is a bit different than previously 8 years ago, at which time I experienced what was more of an anxious depression - high on anxiety and panic. In the past few months, I am experiencing a more andhedonic depression with anxiety. The anhedonia is pretty scary. Oh well, I have to continue to have faith that things will get better, and that this too shall pass.
>
> Tamara
>
>
> > I would think that trying the Paxil at higher dosages would certainly worth a shot, given it's positive history for you...
>
>

Tamara,

I don't think that the SSRIs tend to be very good for anergic type depressions. They may have a depressive effect on dopamine. I think that serotonin and dopamine work like a see saw with one of them on each side. If increasing Paxil doesn't work for you, then I think you are wise to look at other options. If I were you I'd look into medications that target norepineprhine and/or dopamine. Have you ever considered Wellbutrin? I'm sure that Sad Panda and some of the others here who know a lot about the TCAs will give you more information on them. Targeting dopamine alone is more complicated and probably not your next step.

Kara


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poster:karaS thread:409656
URL: http://www.dr-bob.org/babble/20041029/msgs/409696.html