Posted by RetiredYoung on October 31, 2004, at 10:28:40
In reply to Re: Tricyclics and SSRI augmentation, posted by linkadge on October 31, 2004, at 9:57:00
Actually, I'm finding the clomipramine to have somewhat strong effects on norepinephrine. My heart rate is way up, which has been the case with every medication I've taken that impacts NE (eg Straterra, Effexor, and Pamelor). Another side effect is frequent urination. Plus the tricyclic goodies like dry mouth.
Bottom line for me is that energy/motivation wise, I'm doing pretty good now. It's the sadness/hopelessness/worthlessness depression feelings that are at issue for me.
FYI, I was on Lexapro for two years until recently. It began pooping out and I was losing more and more energy, the longer I was on it. We tried augmenting with Provigil and Adderall with only short term good results. Basically, the stimulants worked great initially, but then they either stopped working (Provigil) or "overflowed" my norepinephrine/dopamine systems causing bad anxiety, nervousness, etc.
So, I started on the clomipramine in August. We wanted to try a pure tricyclic to see what it's effecys might be on my other (definitely related) health problem: daily tension headaches.
poster:RetiredYoung
thread:409503
URL: http://www.dr-bob.org/babble/20041029/msgs/409525.html