Posted by SLS on October 28, 2004, at 11:19:10
In reply to Re: Riluzole (Rilutek) - glutamate/calcium?, posted by dove on October 28, 2004, at 9:49:32
> Is this glutamate increasing calcium influx into the neuron a possible reason for meds such as verapamil (calcium channel blocker) working for some bipolar's depression?
> Thus, giving Rilutek (riluzole) the hypothetical potential for antidepressant effects (especially in bipolars).
> random thoughts....
They're pretty good ones.
Right now, my justification for trying riluzole is more emipirical than theoretical. I responded partially to both Lamictal and Namenda. These drugs reduce glutamatergic activity, as does riluzole.
Thanks for your input.
I hope all is well with you.