Posted by SLS on October 26, 2004, at 16:07:50
In reply to Is Trazodone an SSRI?, posted by redscarlet on October 26, 2004, at 15:50:24
Trazodone (Desyrel) is a phenylpiperazine. It is a weak inhibitor of serotonin (5-HT) reuptake, but it does other things too. It is not really selective. It is also an antagonist of 5-HT2a and NE alpha-1 receptors. Its metabolite, mCPP, is an agonist of 5-HT2b and 5-HT2c receptors. Some literatures states that trazodone is devoid of anticholinergic side effects, others describe mild effects.
- Scott
poster:SLS
thread:407541
URL: http://www.dr-bob.org/babble/20041024/msgs/407555.html