Posted by Carlos C on October 22, 2004, at 18:13:37
In reply to Re: Pdoc finally prescribed GHB (Xyrem)! » Carlos C, posted by jboud24 on October 22, 2004, at 15:26:45
> How would you compare the xyrem to benzodiazepines, if you have ever taken them. If you would compare their sedative, hypnotic, and anti-anxiety qualities. Of course, any input would be appreciated.
I had a lengthy report written out for you ...I'm so clumbsy! I hit the refresh button by mistake and POOF! I'll try to re-write it. Hopefully I don't miss too much...
I have used benzodiazepines before. I've used both Xanax and Klonopin for a while. Along with a host of SSRIs, SNRIs, and MAOIs. Simply put I find it simply blows them all (anti-depressants) away! It has a comfortable calming effect with a slight, pleasant hint of euphoria. The best anti-anxiety and anti-depressant I've ever used. The only bad part is it's very short half-life. I find myself having to redose a couple times a day. It isn't all that bad. The positive effects most definitely out weigh this slight inconvienence. Orpham medical the distributors of Xyrem (Sodium Oxybate/GHB) are currently working on this. The rep told me hopefully by sometime next year they may have something.
The best part is that GHB is actually a nutrient. There are plenty of studies that show it has many positive effects on the body. I've been using it for about 3 years and my health has only improved. I've had blood work done on and off of daily use. My doctor says my health is actually BETTER while on it. It has no rebounding effect like benzo's do either. After discontinuing use conditions typically do not intensify. My anxiety and depression never come back worse. I've also noticed no build-up of tolerance.
Like most meds dosing is very user specific. Narcolepsy and insomnia patients usually take 4.5 grams x2 a night. The dose is about half that to get it's anti-anxiety and anti-depressant effects. I usually use 2.6 grams 3-5 a day.
You could check out some things from Dr. Ward Dean. He is a GHB expert. He has tons of knowledge of it and has done many studies. He has prescribed it to many of his patients.