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Re: Cymbalta-Need infor -Urinary Hesitation

Posted by King Vultan on October 22, 2004, at 17:18:45

In reply to Re: Cymbalta-Need infor -Urinary Hesitation, posted by Kristel on October 22, 2004, at 15:45:11

> Yes. Despite that to urinate frequently and urinary hesitation are not the same, their underlying physiological cause might be the same. Such side effects of the drugs that affect noradrenaline are casued by noradrenaline over stimulating the alpha 1 adrenergic receptors in the prostate. This can tighten it up and enlarge it a bit. This in turn can cause to either hesitation or frequent urination or both.
> Kristel.

Right. In some cases, the stimulation of the alpha-1 receptors can cause the muscles of the prostate to constrict and limit urinary flow. Thus, a fellow might not be able to empty his bladder other than a small amount that is basically forced out from the pressure inside the bladder, aided by whatever force he can exert. The bladder is still mostly full--or at least not completely empty, depending on how severe the problem is--so it then refills more quickly than normal, forcing the man to go again, and this cycle repeats itself. An alpha-1 blocker, such as doxazosin, prazosin, or terazosin, can be an aid in these situations.





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