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Re: Cymbalta (duloxetine) - report SLS

Posted by michael on September 4, 2004, at 13:54:25

In reply to Re: Cymbalta (duloxetine) - report, posted by SLS on September 4, 2004, at 8:05:21

> 9/4/2004
> Day 16 (6 days at 30mg; 10 days at 60mg)
> 60mg (30mg b.i.d.)
> I can't say that I feel any improvement, but I don't feel worse either. That's positive. On Wednesday, I definitely felt an improvement in depression that is not part of the normal course of my illness. I attribute it to Cymbalta. Unfortunately, most of that has disappeared. If there is anything positive going on, it is difficult to discern, but I believe I still have reason to be optimistic.
> Regarding side effects, there is still some mild sleepiness, but it is gradually disappearing. I have noticed a bit of hesitency in urination and perhaps some restricted flow.
> Cymbalta still feels very clean. I can't say that it is similar to any of the other drugs mentioned along this thread because I hardly know that I am taking it. Most of the others made themselves known by producing some kind of perceptible cognitive effect. This is producing none. Maybe I'm not taking enough.
> - Scott

Hey Scott -

Just a quick thought to muddy the waters for you...

The transient improvement that you mentioned on Wednesday - might there be a "window" / range such that going to a higher dose might nullify the positive effects?

I know - impossible to know now... and I'd keep increasing the does myself, just to see if that makes it work better. But just thought I'd mention it, in case you may want to explore that later, should escalating the dose not help as much as you're hoping for. Just an idea... And thanks for your "off-PB" feedback recently.

As always, wishing you the best of luck~!
(also as always, feel free to, but no reply necessary)





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