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Re: Zyprexa attributes gardenergirl

Posted by chemist on August 30, 2004, at 21:57:50

In reply to Re: Zyprexa attributes, posted by gardenergirl on August 30, 2004, at 21:41:43

> Isn't Zyprexa also known for weight gain and increased risk of developing type II diabetes?
> gg

hi gg...the white-paper indicates weight gain, and i have one m.s. (not a great one, and funded by ortho-mcneil: C. B. Nemeroff, J. Clin. Psychiatry 64:5 pp. 532-539, May 2003) on my desk that states that mean weight gain for olanzapine (zyprexa) from a meta-analysis of 81 journal articles is 9.22 lb. (4.15 kg) and that ``evidence is mounting that antipsychotic treatment may impair glucose tolerance'' and that the drugs implicated are chlorpromazine, clozapine, and olanzapine. i do recall there being a flurry of diabetes mellitus risk, but do not have the refs on hand or in mind. be glad to track 'em down, if you'd like, to confirm/deny.....all the best, chemist




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