Psycho-Babble Medication | about biological treatments | Framed
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Re: A possible explaination.

Posted by linkadge on August 29, 2004, at 18:34:18

In reply to Re: A possible explaination. owensmar, posted by linkadge on August 29, 2004, at 18:12:35

I tend to think of the d3 activation as the "personal pleasure". I have a feeling that it makes pleasure seem very "personal" and "your own", and "complete/satisfying".

I think that actiavtion of other dopamine receptors *can* increase pleasure but they tend to give that feeling of "uncompleteness", or "wanting more". That feeling of being good, but its "not yours", or its "just out of reach".

This is of course pure speculation, but I have formulated some hunches based on the combo's I've tried. The AP's like seroquel/zyprexa 'low dose'
imroved anhedonia and make pleasure seem more complete and personal, while the stimulants seemed to make thinks more *interesting* but gave that aweful pressured feeling. Its hard to describe but its like "to much is given much is expected" Perhaps its just an extension of my mild psychosis :) but stimulants tend to make me feel more 'universally responsable' and 'guilty'.

The d2 receptor is highly involved in psychosis
I think that d2 activation can create that deep feeling of presence, almost making things 'super real'. I think it can boost feelings of significance, making your actions feel more significant and important. It can bring meaning to your life, but sometimes too much meaning or imagined created meaning. I think that d2 activation is too deep for me.

I think that d1 activation is more involved in feelings of creating logical order. It activates parts of the brain that seek structure order symmetry etc. I think that d1 activation brings pleasure from completion.

Again this is certainly not set in stone, but this is some of the ideas I have conjured from some of the reading I have done.

I found seroquel the best of the 3 AP's. It doesn't block the d1 receptor like zyprexa does and left me more motivated. Zyprexa didn't leave me apathetic, but just "unmotivated".





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