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Re: 2nd Q on paradoxical stim. response - z, anybody?

Posted by zeugma on August 28, 2004, at 17:17:54

In reply to Re: 2nd Q on paradoxical stim. response - z, anybody? King Vultan, posted by KaraS on August 27, 2004, at 21:52:02

hi kara,

if Todd is right, then it would take Ritalin about as long as an AD to kick in and have its desired effect (am i correct in assuming this?) btw the NE system has been posited to be in the same state of disequilibrium in melancholic depression, and imipramine has been surmised to work by desensitizing the alpha-2 autoreceptor. Studies to test this hypothesis by adding an alpha-2 antagonist to impramine or other TCA have been inconclusive or outright failures, however. Also, buspirone desensitizes the inhibitory 5HT-1A presynaptic receptor, yet it is commonly regarded as a weak drug at best.





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