Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: The *Real* Truth - zeugma too

Posted by SLS on August 25, 2004, at 7:17:06

In reply to Re: The *Real* Truth - zeugma too » Dave001, posted by zeugma on August 25, 2004, at 5:32:44

> Note that modafinil also causes significant induction of the CYP3A4/5 enzymes, and is an inducer of its own metabolism.
>
> Dave
>
> yes i know that. i take buspirone (30 mg) and clonazepam (1 mg) which could be affected by this. i'm not worried about the buspirone because that drug has such a short half life, and its metabolite (which will increase as a result of enzyme induction)is an alpha 2 antagonist which probably has a therapeutic effect for me. the clonazepam is more serious but i was taking Provigil for over a month at dosages up to 100 mg/day and did not notice increases in anxiety.
>
> the problem is that i'm also taking nortriptyline 100 mg/day and that makes 5 meds taken concurrently which could be very complicated. if anything 3A induction would lower nortriptyline levels slightly. but it's the effect of all 5 that concerns me.

Hi Z.

I see that 3A is a minor pathway for nortriptyline metabolism.

Is there a site on the Internet you use to stay current on CYP450 information?

I have an older program that can compare the interactions of multiple medications. If you list them, I can check them for you.


- Scott

 

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:SLS thread:380561
URL: http://www.dr-bob.org/babble/20040825/msgs/382033.html