Posted by jlbl2l on August 21, 2004, at 20:23:30
In reply to Re: Sleeping drugs » jlbl2l, posted by Larry Hoover on August 21, 2004, at 12:40:19
Larry,
This study just verifies what i am saying. benzos decrease delta wave activity (slow wave sleep 3/4) and increase beta wave activity (stage 2).
the non-benzodizepine hypnotics "z drugs" generally keep the sleep spindle in place, at least in the case with zolpidem - and it basically says zolpidem was less disruptive in this study - and i can bring up many studies that say ambien (zoldipem) maintains the sleep spindle without majorly disrupting the sleep stages.
I have no idea how you conclude this study says there isn't supression of slow wave sleep by the benzodizepines.
"decreased delta activity resulted mainly from a decrease in wave amplitude"
"Delta suppression increased with repeated drug administration "
"increased sigma and beta activity were produced by increased wave incidence"
What more is there to say, do I not understand your post correctly? benzodizepines suppress slow wave activity (delta waves..) and increase stage 2 sleep (beta) that is what these studies say.
If you want to talk about the non-benzodizepine hypnotic ambien, let me know, as that is a different class and we can pull up numerous studies on it if you like.
all the best,
jlbl2l
poster:jlbl2l
thread:380051
URL: http://www.dr-bob.org/babble/20040821/msgs/380575.html