Posted by Ame Sans Vie on August 12, 2004, at 12:06:43
In reply to Re: Somebody! I need advice fast!, posted by King Vultan on August 12, 2004, at 10:22:51
> I guess I would vote for desipramine, as my own experience with nortriptyline was that it was too sedating. Desipramine is definitely more activating and because it works so heavily on norepinephrine, you may find it has a tendency to reduce your need for sleep.
I was sort of leaning toward desipramine as well... I certainly don't want to take anything that is likely to sedate me (i.e., nortriptyline) as I have enough trouble staying awake as is. I can't remember ever having a medication-provoked panic attack, so I think I'd be safe with Wellbutrin (especially with 12mg of clonazepam on board each day). But I remember the past few times I tried it I couldn't get through the first two weeks solely because of that dry mouth which drove me crazy. I know there's that cholinergic medication Salgan that causes saliva to be secreted and it's often used in cases like those, but I simply can't afford *another* medication.
However, desipramine does worry me a bit because I've heard of more than one person experiencing terribly painful inability to urinate that lasted several days, due to the anticholinergia. I went through that once with Gabitril, and I don't think I'd dare take that gamble again!
Damn, this is a tough decision...
> It does have a weak histamine blockade that some people are sensitive to, but this is going to generally be overpowered by its NE reuptake blockade.
My brain doesn't know the meaning of "antihistamine", lol. I guess I'm just a complete screw up -- 200mg of Benadryl and I'm wired. <shrug>
>Some people feel nortriptyline is a better antidepressant, and desipramine is better for ADD, but this was certainly not my experience. YMMV.
Thanks a bunch for your input! I'll just keep pondering and researching for the next three hours I suppose, lol.
~Michael
poster:Ame Sans Vie
thread:376819
URL: http://www.dr-bob.org/babble/20040811/msgs/376858.html