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Re: All current and former NARDIL users!! Need advice » Michael Bell

Posted by King Vultan on August 9, 2004, at 8:03:57

In reply to All current and former NARDIL users!! Need advice, posted by Michael Bell on August 8, 2004, at 21:01:46

> I've reached a crossroads in my life where I need to determine what my next long-term therapy med for SP is going to be. The Klonopin has been great for anxiety, but it's been making me more and more anhedonic and dysthymic, and I can't take it anymore. Using adjunctive meds like adderall or amisulpride or prozac have had minimal beneficial effects if any.
>
> I once tried Nardil for about 3 weeks, and it was the best med for SP I've ever tried (in combo with Klonopin). But the side effect profile scared me too much.
>
> Now I've come full circle, and I need your advice please. If you've ever used Nardil, especially for SP, please answer the following:
>
> 1) How real is the hypertensive crisis risk if I follow the diet?
>

I would say it is close to zero. The only thing is you might get tripped up eating some spoiled food. However, Nardil is more forgiving than Parnate as far as hypertensive crises in general.


> 2) What is the best med to block a hypertensive crisis from occurring?

Nifedipene has both proponents and opponents, but my own conclusion after studying the arguments is that there are for more pros than cons than associated with it. I carry two 10 mg capsules of nifedipine at all times, but more as a psychological security blanket than anything else. If they obey the restrictions, Nardil users should really never have any need to actually use this.

>
> 3) Do the sexual side effects ever go away?

I would not be real optimistic that they do, unless you are able to find relief at a lower dosage that is still therapeutic for your SP. However, I was on Nardil for only a little over five months altogether.

>
> 4) Finally, what is your overall feeling regarding Nardil as long term treatment for SP?
>

It's the best one I've tried personally, with my ranking the drugs I've tried like this:

1) Nardil
2 (tie) desipramine, Vivactil
4) nortriptyline
5) Strattera
6) Wellbutrin
7) Effexor
8) Zoloft
9) Prozac
10) Provigil

I think the reason Nardil works so well is that it is very serotonergic like the SSRIs, it has an effect on GABA somewhat like the benzos do, and it also has a strong effect on norepinephrine--which I am convinced is important in my case, anyway, based on the very positive impact the TCAs had on my SP.

> Thanks so much for your help. I hope everyone is making progress towards the ultimate goal.

I sure feel like I'm making progress, and this group has been a big help.

Todd


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poster:King Vultan thread:375433
URL: http://www.dr-bob.org/babble/20040805/msgs/375551.html